久久久国产一区二区_欧美在线小视频_高清一区二区三区_久久综合久久久_成人久久久久久久久_亚洲精品视

上海非利加實(shí)業(yè)有限公司Logo

熱門(mén)詞: 進(jìn)口電動(dòng)溫度調(diào)節(jié)閥結(jié)構(gòu)圖|進(jìn)口電動(dòng)溫度調(diào)節(jié)閥數(shù)據(jù)表進(jìn)口電動(dòng)高溫調(diào)節(jié)閥-德國(guó)進(jìn)口電動(dòng)高溫法蘭調(diào)節(jié)閥進(jìn)口電動(dòng)蒸汽調(diào)節(jié)閥-德國(guó)進(jìn)口電動(dòng)蒸汽調(diào)節(jié)閥

當(dāng)前位置: 首頁(yè) > 所有品牌 > Alnylam
Alnylam
Alnylam Alnylam

美國(guó)同業(yè)Alnylam Pharmaceuticals Inc.(ALNY)  
Alnylam是一家生物制藥公司,基于 RNA干擾 或RNAi開(kāi)發(fā)新穎的療法。公司正在將其治療方面的專(zhuān)門(mén)技術(shù)應(yīng)用于RNAi,以滿(mǎn)足重大的醫(yī)療需求,而目前的主要藥物類(lèi)別小分子或抗體藥物無(wú)法滿(mǎn)足其中的許多需求。Alnylam正在率先將RNAi轉(zhuǎn)化為一類(lèi)新的創(chuàng)新性藥物,其同儕審評(píng)的研究成果已在全世界一流的科學(xué)雜志包括《自然》、《自然藥物》和《細(xì)胞》中發(fā)表。公司正在運(yùn)用這些能力,建立一種廣泛的 RNAi療法管道;其最前沿的計(jì)劃是治療呼吸道合胞病毒(RSV)感染的二期人體臨床試驗(yàn),該試驗(yàn)與Cubist和Kyowa Hakko合作進(jìn)行。此外,公司正在開(kāi)發(fā)RNAi療法,治療多種疾病,包括肝癌、高膽固醇血癥、亨廷頓舞蹈病和TTR 淀粉樣變性病。公司在RNAi方面的基本專(zhuān)利、技術(shù)和專(zhuān)門(mén)知識(shí)上占據(jù)領(lǐng)先地位,從而得以與Medtronic、Novartis、Biogen Idec、Roche、Takeda、Kyowa Hakko Kirin和Cubist等首屈一指的公司結(jié)為主要聯(lián)盟。為了反映公司對(duì)主要的科學(xué)、臨床和商業(yè)倡議的看法,Alnylam在2008年1月建立“RNAi 2010”,包括公司的以下規(guī)劃:顯著擴(kuò)展 RNAi療法給藥方法解決方案范圍,擁有四個(gè)或更多的臨床開(kāi)發(fā)規(guī)劃,建立四項(xiàng)或更多的主要業(yè)務(wù)新合作關(guān)系,所有這一切都在2010年年底之前完成。Alnylam和Isis共同擁有Regulus Therapeutics Inc.,Regulus Therapeutics Inc.側(cè)重于微RNA療法的發(fā)現(xiàn)、開(kāi)發(fā)和商業(yè)化。Alnylam于2002年創(chuàng)建,總部設(shè)于麻省劍橋。

 

Phil Sharp

Alnylam的創(chuàng)始人之一

美國(guó)生物學(xué)家菲利普·夏普的主要研究領(lǐng)域是植物學(xué)、生物化學(xué)、核糖核酸調(diào)控。他是獲得美國(guó)國(guó)內(nèi)院士稱(chēng)號(hào)最多的科學(xué)家之一,因發(fā)現(xiàn)斷裂基因而獲得1993年諾貝爾生理學(xué)或醫(yī)學(xué)獎(jiǎng)。他曾任麻省理工學(xué)院生物系主任和癌癥研究中心主任。夏普教授在生物醫(yī)學(xué)領(lǐng)域作出了巨大貢獻(xiàn),在國(guó)際上享有盛譽(yù)。他因開(kāi)發(fā)新的醫(yī)藥產(chǎn)品而獲得美國(guó)國(guó)家技術(shù)獎(jiǎng)?wù)隆D壳埃闹饕芯糠较驗(yàn)镽NA干擾素,為治療疾病帶來(lái)新思路。


Alnylam is developing an entirely new class of innovative medicines based on a breakthrough discovery in biology known as RNA interference, or RNAi. With RNAi technology, we have the opportunity to treat disease and impact the lives of patients in a fundamentally new way by silencing disease-causing genes upstream of today's medicines.

The meaning of our name, Alnylam(al-NIGH-lam)
Located in the constellation Orion, Alnylam is the name of the center star of Orion's belt. The star has a luminosity that is 250,000 times greater than the sun, representative of the potential strength that RNAi therapeutics could bring to bear for human health.
As scientists continue to investigate the human genome, where we now have the complete genetic sequence, there have been remarkable developments in the understanding of disease and consequently a large increase in the number of molecular disease targets to impact a broad range of human disease. Paradoxically, with all these new opportunities to significantly impact disease, the challenge for the industry has been that today's therapeutic modalities, such as small molecules and monoclonal antibodies cannot access most (~70%-80%) of these new disease targets. With RNAi, we can target virtually any gene in the genome involved in the causal pathway of disease. The possibility of targeting these previously "undruggable" targets with RNAi is transformative for new drug discovery.

We have made very significant strides in the development and advancement of RNAi therapeutics. For example, in 2004. Alnylam scientists demonstrated the ability to deliver RNAi therapeutics in mice mice achieving a desired therapeutic effect, and in 2006, we achieved similar results in non-human primates; both of these landmark studies were published in the journal Nature. In 2008, with our Phase II GEMINI study, we showed for the first time that RNAi works in man when we demonstrated that an RNAi therapeutic achieved statistically significant efficacy in a randomized, double-blind, placebo-controlled human clinical trial. By all measures, this represents clear and very rapid progress.

Our strategy at Alnylam is to lead the translation of the science of RNAi into a robust drug discovery capability and to build a significant product pipeline of innovative medicines that we commercialize alone or with our partners. The pace of biomedical discovery is faster than ever and the hunger for innovative medicines is greater than ever. This environment, when combined with Alnylam's unparalleled intellectual property position for RNAi therapeutics and our industry-leading alliances, creates a unique opportunity for Alnylam to build a leading biopharmaceutical company.
 

關(guān)于我們客戶(hù)服務(wù)產(chǎn)品分類(lèi)法律聲明
主站蜘蛛池模板: 中文字幕三区 | 麻豆视频一区二区 | 高清国产美女一级a毛片 | 一区二区亚洲视频 | 亚洲精品高清在线观看 | 国产一区二区三区视频在线观看 | 欧美一区精品二区三区 | 亚洲欧美在线视频 | 日韩在线视频在线观看 | 亚洲欧美字幕 | 久久精品综合国产二区 | 91福利国产在线观一区二区 | 看全色黄大色大片免费久久久 | 国产成人精品一区二区三区 | 国产成人乱码一区二区三区 | 可以免费观看的毛片 | 国内高清久久久久久久久 | 欧美 日韩 国产 在线 | 国产精选视频在线观看 | 韩国精品一区二区久久 | 91欧美激情一区二区三区成人 | 欧美日韩专区 | 国产 欧美 日韩 在线 | 欧洲精品欧美精品 | 亚欧成人毛片一区二区三区四区 | 国产欧美日 | 欧美日韩免费一区二区三区 | 日韩精品国产精品 | 国产免费视屏 | 亚洲国产一区二区三区在线观看 | 欧美精品国产精品 | 九九爱精品视频 | 亚洲视频在线观 | 日本欧美国产精品第一页久久 | 欧美大色 | 亚洲精品国产综合一线久久 | 久久无码精品一区二区三区 | 最新国产在线观看 | 天堂亚洲欧美日韩一区二区 | 欧美日韩亚洲一区二区三区在线观看 | 日韩高清欧美 |